李冠楠
发布时间： 2016-04-08 20:14:32 已阅读：
李冠楠，1985年生，讲师，遗传学专业。博士后研究方向为食品营养学，当前主要从事家蚕益生菌、微生物-昆虫宿主互作和毒理学等方面研究。以家蚕为模式生物探究兼性次级共生体对宿主生长发育和营养代谢的作用机理；此外，同时研究有毒物质对家蚕肠内稳态、免疫扰动和血液循环代谢物的损害机制。以第一作者发表SCI论文10篇（其中中科院一区论文2篇，二区论文4篇），曾主持或参与国家级和省部级项目10余项，在研校级项目1项，获得国家已授权发明专利1项。目前担任中文核心期刊《食品研究与开发》和《食品发酵工业》等特邀审稿人，以及《Microbiome》、《Journal of Advanced Research》、《Scientific Reports》、《BMC Genomics》、《BMC Microbiology》、《Archives of Microbiology》、《FEMS Microbiology Letters》和《Journal of Polymers and the Environment》等SCI期刊审稿人。
教育及研究经历
2019.05-2020.06，新加坡国立大学，食品科学与技术学院，博士后
2017.05-2020.09，西南大学，畜牧学博士后流动站，特种动物经济饲养方向
2010.09-2015.12，西南大学，生物技术学院，遗传学专业，理学博士（硕博连读）
2005.09-2009.06，西南大学，生命科学学院，生物工程专业，工学学士
代表性研究成果
SCI期刊：
1. Li G.N., Zheng X., Zhu Y., et al. In-depth insights into the disruption of the microbiota-gut-blood barrier of hosts by fluoride. Science of The Total Environment. 2022, 838: 156220. (IF2021=10.753; 中科院一区)
2. Li G.N., Shi M., Zhao S., et al. Toxicity response of silkworm intestine to Bacillus cereus SW7-1 pathogen. Science of the Total Environment. 2019, 692: 1282-1290. (IF2019=6.551；中科院大类一区)
3. Li G.N., Zheng X., Zhu Y., et al. Bacillus symbiont drives alterations in intestinal microbiota and circulating metabolites of lepidopteran host. Environmental Microbiology. 2022; 24: 4049-4064. (IF2021=5.476；中科院二区)
4. Li G.N., Xia X.J., Zhao S., et al. The physiological and toxicological effects of antibiotics on an interspecies insect model. Chemosphere. 2020, 248: 126019. (IF2020=7.086；中科院二区)
5. Li G.N., et al. Probiotic Bacillus subtilis contributes to the modulation of gut microbiota and blood metabolic profile of hosts. Comp Biochem Physiol C Toxicol Pharmacol. 2023; 272:109712. (IF2022=3.9；中科院二区)
6. Li G.N., Xia X.J., Zhao H.H., et al. Intestinal microecology associated with fluoride resistance capability of the silkworm (Bombyx mori L.). Applied Microbiology and Biotechnology. 2016, 100(15): 6715-6724. (IF2016=3.420；中科院大类二区)
7. Li G.N., Shi M., Zhao S., et al. RNA-Seq comparative analysis reveals the response mechanism of Enterococcus faecalis TV4 under fluoride exposure. GENE. 2019, 726: 144197. (IF2019=2.984；中科院大类三区)
8. Li G.N., Cai M., Zheng X., et al. Impact of disinfectants on the intestinal bacterial symbionts and immunity of silkworm (Bombyx mori). Environmental Science and Pollution Research. 2022; 29:79545-79554. (IF2021=5.190；中科院三区)
9. Li G.N., Xiao Y., Leng J., et al. Beneficial efficacy and mode of action of probiotic Bacillus subtilis SWL−19 on the silkworm (Bombyx mori L.). Symbiosis. 2024, https://doi.org/10.1007/s13199-024-00986-4. (IF2023=2.5；中科院三区)
10. Li G.N., Xia X.J., Zhao H.H., et al. Identification and characterization of Bacillus cereus SW7-1 in Bombyx mori (Lepidoptera: Bombycidae). Journal of Insect Science. 2015, 15(1): 136-140. (IF2015=0.650；中科院大类三区)
11. Xia XJ, Li G.N., Xing Y.X., et al. Antioxidant activity of whole grain highland hull-less barley and its effect on liver protein expression profiles in rats fed with high-fat diets. European Journal of Nutrition, 2017, 57: 2201-2208. (IF2017=4.423；中科院大类二区；共同一作)
12. SENDEGYA P., Li G.N., Zhao H.H., et al. Effect of fluoride on the midgut proteins of T6 and 734 strains of the silkworm (Bombyx mori). Fluoride. 49(2):102-111. (IF2015=0.797；中科院大类四区；共同一作)
13. Xia, X., Li, G.N., Dong, Q.L., et al. Endothelial progenitor cells as an emerging cardiovascular risk factor in the field of food and nutrition research: advances and challenges. Crit Rev Food Sci Nutr. 2023, 21:1-18. (IF2022=10.2; 中科院一区)
14. Xia X.J., Li G.N., Ding Y.B., Ren T.Y., Zheng J., Kan J.Q.* Effect of whole grain Qingke (Tibetan Hordeum vulgare L. Zangqing 320) on serum lipid levels and intestinal microbiota of rats under high-fat diet. Journal of Agricultural and Food Chemistry. 2017, 65(13): 2686–2693. (IF2015= 2.857; 中科院大类一区)
15. Xia X.J., Li G.N., Zheng J., et al. Immune activity of sweet potato (Ipomoea batatas L.) glycoprotein after enzymatic and chemical modifications. Food & Function. 2015, 6(6): 2026-202. (IF=2.686；中科院大类一区)
16. Xia XJ, Li G.N., Song JX, et al. Hypocholesterolaemic effect of whole-grain highland hull-less barley in rats fed a high-fat diet. British of Journal Nutrition, 2018, 119: 1102-1110. (IF2017=3.706；中科院大类二区)
17. Xia X.J., Xing Y.X., Li G.N., et al. Antioxidant activity of whole grain Qingke (Tibetan Hordeum vulgare L.) toward oxidative stress in D-galactose induced mouse model. Journal of Functional Foods, 2018, 45: 355-362. (IF=3.47；中科院大类二区)
18. Xia X.J., Li G.N., Zheng J., Ran C.X., Kan J.Q. Biochemical, textural and microstructural changes in whole-soya bean cotyledon sufu during fermentation. International Journal of Food Science and Technology. 2014, 49(8): 1834-1841. (IF2014=1.504；中科院大类二区)
19. Xia X.J., Li G.N., Liao F.R., et al. Granular structure and physicochemical properties of starches from amaranth grain. International Journal of Food Properties. 2015, 18(5): 1029-1037. (IF2015=1.586；中科院大类四区)
20. Long Y.H., Li J.R., Zhao T.F., Li G.N., Zhu Y. A new arylalkylamine N-acetyltransferase in silkworm (Bombyx mori) affects integument pigmentation. Applied Biochemistry and Biotechnology. 2015, 175(7): 3447-3457. (IF2015=1.606；中科院四区)
21. Tang W.C., Xiao Y.Y., Li G.N., et al. Analysis of digital gene expression profiling in the gonad of male silkworms (Bombyx mori) under fluoride stress. Ecotoxicology and Environmental Safety, 2018, 153: 127-134. (IF2018=4.527；中科院大类二区)
22. Zheng X., Liu F.D., Shi M., Li S., Xie X.F., Li G.N., Zhang X.N., Zhu Y. Transcriptome analysis of the reproduction of silkworm (Bombyx mori) under dimethoate stress. Pesticide Biochemistry and Physiology. 2022, 183: 105081. (IF2021=3.963；中科院一区)
中文期刊：
中文期刊：
1.夏雪娟，陈莉敏，李冠楠. 乳杆菌对肠内分泌细胞胰高血糖素样肽3331分泌的影响. 食品发酵与工业. 2023. DOI: 10.13995/j.cnki.11-1802/ts.035891. (《中国科技期刊卓越行动计划入选项目》重点期刊；通讯作者)
2.李冠楠，夏雪娟，SENDEGYA Parfait等. 蚕用益生芽孢杆菌SWL-19的筛选鉴定及其对肠道菌群多样性的影响. 中国农业科学. 2015, 48(9): 1845-1853.
3李冠楠，夏雪娟，SENDEGYA Parfait等. 氟化物对家蚕肠道微生物菌群的影响. 微生物学报. 2015, 55(7): 926-934.
4李冠楠，夏雪娟，隆耀航等. 抗菌肽的研究进展及其应用. 动物营养学报. 2014, 26(1): 17-25.
5.李冠楠，夏雪娟，赵欢欢等. 氟化物对家蚕耐氟和氟敏品种肠道中留存产酶菌群落组成和多样性的影响. 昆虫学报. 2014, 57(2): 187-193.
6.石敏，李冠楠，郑茜等. 乐果对家蚕生殖腺及氧化应激反应的影响. 昆虫学报. 2019, 62(10): 1186-1196.
7.夏雪娟，李冠楠，廖丽婷等. 基于Miseq测序技术分析高脂膳食对不同性别SD大鼠盲肠菌群的影响. 中国食品学报. 2019, 19(01): 223-232.
8.何石宝，李冠楠，郭东东等. 果蝇求偶行为分子调控机制的研究进展. 中国生物工程杂志. 2015， 35(10): 78-85.
9.阚建全，夏雪娟，李冠楠等. 加工处理对甘薯糖蛋白免疫调节和降胆固醇功能的影响. 食品科学. 2015, 36(7): 194-199.
10.米智，阮成龙，李冠楠等. 家蚕氟中毒后中肠NADPH-细胞色素P450还原酶和NADPH-细胞色素C还原酶活性的变化. 蚕业科学. 2012, 38(1): 0102-0108.
获得的专利：
朱勇*，李冠楠等，《蚕用益生枯草芽孢杆菌SWL-19及其应用》. 2018-02-06, 中国发明专利, ZL 201510119974.6.
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