邹云龙
发布时间: 2019-04-08 20:03:25 已阅读:
(2024年4月拍摄)
邹云龙
博士,副教授,硕导。2018年1月博士毕业于中国农业大学 生物学院 生物化学与分子生物学专业。
科研项目:主持国家自然科学基金青年基金项目、中央高校基本科研业务费
研究方向关键词:基因编辑、昆虫化学感受、家蚕发育生物学
主要科研贡献:
(1)高效基因编辑工具的开发与优化。在家蚕中,建立了高效的基于核糖核蛋白的CRISPR/Cas9和CRISPR/Cas12a (Cpf1) 基因编辑系统。利用遗传修饰手段(基因编辑、转基因)解析重要基因的功能、探究调控机制、创制育种素材。
(2)众所周知,家蚕主要以桑叶为食,对桑叶具有特殊的偏好。我们对其遗传基础及调控机制进行了深入研究,挖掘了多个参与家蚕食性调控的嗅觉受体、味觉受体、转录因子,并通过基因编辑创制了对人工饲料优异适应性的育种素材。
讲授课程:《基因工程》、《遗传学》(英文)、《生命科学前沿讲座》(主持)
工作经历:
2023年7月 — 至今 蚕桑纺织与生物质科学学院 副教授
2018年7月 — 2023年7月 蚕桑纺织与生物质科学学院 讲师
发表论文 (#共同一作, *通讯作者):
[1] Yunlong Zou; Wentao Wu; Tianfu Luo; Yuxia Tang; Hai Hu; Aijun Ye; Lifeng Xu; Fangyin Dai*; Xiaoling Tong*. Disruption of Zfh3 abolishes mulberry-specific monophagy in silkworm larvae, Insect Science, 2024, doi: 10.1111/1744-7917.13354.
[2] Yun-Long Zou#; Xin Ding#; Li Zhang#; Li-Feng Xu; Shu-Bo Liang; Hai Hu; Fang-Yin Dai; Xiao-Ling Tong*. Bmmp influences wing morphology by regulating anterior-posterior and proximal-distal axes development, Insect Science, 2022, 29(6):1569-1582.
[3] Yun-long Zou; Ai-jun Ye; Shuo Liu; Wen-tao Wu; Li-feng Xu; Fang-yin Dai; Xiao-ling Tong*. Expansion of targetable sites for the ribonucleoprotein-based CRISPR/Cas9 system in the silkworm Bombyx mori, BMC Biotechnology, 2021, 21(1): 54
[4] Yunlong Zou; Haiyang Hao; Ning Li; Qiuyan Li*. Establishment and characterization of immortalized porcine neonatal hepatocytes without the use of viral components, In Vitro Cellular & Developmental Biology-Animal, 2020, 56 (1): 75-84
[5] ZOU Yun-long; LI Zhi-yuan; ZOU Yun-jing; HAO Hai-yang; HU Jia-xiang; LI Ning; LI Qiu-yan*. Generation of pigs with a Belgian Blue mutation in MSTN using CRISPR/Cpf1-assisted ssODN-mediated homologous recombination, Journal of Integrative Agriculture, 2019, 18(6): 1329-1336
[6] Yunlong Zou; Zhiyuan Li; Yunjing Zou; Haiyang Hao; Ning Li; Qiuyan Li*. An FBXO40 knockout generated by CRISPR/Cas9 causes muscle hypertrophy in pigs without detectable pathological effects, Biochemical and Biophysical Research Communications, 2018, 498(4): 940-945
[7] Yunlong Zou; Yanjun Dong; Qingyong Meng; Yaofeng Zhao*; Ning Li*. Incorporation of a skeletal muscle-specific enhancer in the regulatory region of Igf1 upregulates IGF1 expression and induces skeletal muscle hypertrophy, Scientific Reports, 2018, 8(1): 2781
[8] Tingting Gai#; Xiaoling Tong#*; Minjin Han; Chunlin Li; Chunyan Fang; Yunlong Zou; Hai Hu; Hui Xiang; Zhonghuai Xiang; Cheng Lu; Fangyin Dai*. Cocoonase is indispensable for Lepidoptera insects breaking the sealed cocoon, PLoS Genetics, 2020, 16(9)
[9] Jingyao Chen; Haitao Wang; Jianhui Bai; Wenjie Liu; Xiaojuan Liu; Dawei Yu; Tao Feng; Zhaolin Sun; Linlin Zhang; Linyuan Ma; Yiqing Hu; Yunlong Zou; Tan Tan; Jie Zhong; Man Hu; Xiaofei Bai; Dengke Pan; Yiming Xing; Yaofeng Zhao; Kegong Tian*; Xiaoxiang Hu*; Ning Li*. Generation of Pigs Resistant to Highly Pathogenic-Porcine Reproductive and Respiratory Syndrome Virus through Gene Editing of CD163, International Journal of Biological Sciences, 2019, 15(2): 481-492
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