邹云龙

邹云龙

博士，副教授（2023-至今），硕士生导师（2024-至今）。2018年博士毕业于中国农业大学 生物学院 生物化学与分子生物学专业。迄今为止，以第一作者身份在Insect Science、Insect Biochemistry and Molecular Biology、Journal of Integrative Agriculture等国际期刊发表SCI论文9篇。

研究方向关键词：家蚕食性、基因编辑、育种素材创制、分子生物学、遗传学

研究方向：

（1）家蚕食性调控的遗传基础和分子机制解析：家蚕主要以桑叶为食，对其具有特殊的偏好，我们希望对这一现象背后的遗传基础和分子机制进行深入探索，系统挖掘参与家蚕食性调控的气味受体、味觉受体、转录因子等，并通过基因编辑创制人工饲料优异适应性的育种素材。

（2）高效基因编辑工具的开发与应用：在家蚕中，建立高效的基于核糖核蛋白复合体的CRISPR/Cas9和CRISPR/Cas12a (Cpf1) 等基因编辑系统。利用遗传修饰手段（基因编辑、转基因）解析重要基因的功能和分子机制。

讲授课程：《基因工程》、《遗传学》（英文）、《生命科学前沿讲座》（主持）

工作经历：

2023年7月 — 至今              蚕桑纺织与生物质科学学院         副教授

2018年7月 — 2023年7月         蚕桑纺织与生物质科学学院    讲师

科研项目：

1. 国家自然科学基金面上项目，2026-2029，主持

2. 国家自然科学基金青年科学基金项目，2023-2025，主持

3. 中央高校基本科研业务费，2019-2021，主持

发表论文 (^#共同一作, *通讯作者)：

[1] Yunlong Zou^#, Yuxia Tang^#, Wei Li^#, Hai Hu, Minjin Han, Xiaoling Tong, Fangyin Dai*. Odorant and gustatory receptors synergistically modulate feeding behaviors that underlie food preference and consumption in the silkworm, Insect Science, 2026, doi: 10.1111/1744-7917.70225.

[2] Yunlong Zou^#, Aijun Ye^#, Meixin Dong, Yuhao Zhou, Wentao Wu, Yuxia Tang, Hai Hu, Fangyin Dai*, Xiaoling Tong*. Silkworm mutagenesis using a ribonucleoprotein-based CRISPR/Cas12a system, Insect Biochemistry and Molecular Biology, 2025, 182:104329.

[3] Yunlong Zou; Wentao Wu; Tianfu Luo; Yuxia Tang; Hai Hu; Aijun Ye; Lifeng Xu; Fangyin Dai*; Xiaoling Tong*. Disruption of Zfh3 abolishes mulberry-specific monophagy in silkworm larvae, Insect Science, 2024, 31(5):1397-1411.

[4] Yun-Long Zou^#; Xin Ding^#; Li Zhang^#; Li-Feng Xu; Shu-Bo Liang; Hai Hu; Fang-Yin Dai; Xiao-Ling Tong*. Bmmp influences wing morphology by regulating anterior-posterior and proximal-distal axes development, Insect Science, 2022, 29(6):1569-1582.

[5] Yun-long Zou; Ai-jun Ye; Shuo Liu; Wen-tao Wu; Li-feng Xu; Fang-yin Dai; Xiao-ling Tong*. Expansion of targetable sites for the ribonucleoprotein-based CRISPR/Cas9 system in the silkworm Bombyx mori, BMC Biotechnology, 2021, 21(1): 54

[6] Yunlong Zou; Haiyang Hao; Ning Li; Qiuyan Li*. Establishment and characterization of immortalized porcine neonatal hepatocytes without the use of viral components, In Vitro Cellular & Developmental Biology-Animal, 2020, 56 (1): 75-84

[7] ZOU Yun-long; LI Zhi-yuan; ZOU Yun-jing; HAO Hai-yang; HU Jia-xiang; LI Ning; LI Qiu-yan*. Generation of pigs with a Belgian Blue mutation in MSTN using CRISPR/Cpf1-assisted ssODN-mediated homologous recombination, Journal of Integrative Agriculture, 2019, 18(6): 1329-1336

[8] Yunlong Zou; Zhiyuan Li; Yunjing Zou; Haiyang Hao; Ning Li; Qiuyan Li*. An FBXO40 knockout generated by CRISPR/Cas9 causes muscle hypertrophy in pigs without detectable pathological effects, Biochemical and Biophysical Research Communications, 2018, 498(4): 940-945

[9] Yunlong Zou; Yanjun Dong; Qingyong Meng; Yaofeng Zhao*; Ning Li*. Incorporation of a skeletal muscle-specific enhancer in the regulatory region of Igf1 upregulates IGF1 expression and induces skeletal muscle hypertrophy, Scientific Reports, 2018, 8(1): 2781

[10] Tingting Gai^#; Xiaoling Tong^#*; Minjin Han; Chunlin Li; Chunyan Fang; Yunlong Zou; Hai Hu; Hui Xiang; Zhonghuai Xiang; Cheng Lu; Fangyin Dai*. Cocoonase is indispensable for Lepidoptera insects breaking the sealed cocoon, PLoS Genetics, 2020, 16(9)

[11] Jingyao Chen; Haitao Wang; Jianhui Bai; Wenjie Liu; Xiaojuan Liu; Dawei Yu; Tao Feng; Zhaolin Sun; Linlin Zhang; Linyuan Ma; Yiqing Hu; Yunlong Zou; Tan Tan; Jie Zhong; Man Hu; Xiaofei Bai; Dengke Pan; Yiming Xing; Yaofeng Zhao; Kegong Tian*; Xiaoxiang Hu*; Ning Li*. Generation of Pigs Resistant to Highly Pathogenic-Porcine Reproductive and Respiratory Syndrome Virus through Gene Editing of CD163, International Journal of Biological Sciences, 2019, 15(2): 481-492

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